The correct answer is 3rd to 2nd Century BCE.Charaka SamhitaIt is also called Caraka-Samhita.It is a detailed text on ancient Indian medicine attributed to Charaka, a practitioner of Ayurveda, India's traditional medical system.Charaka-Samhita, also spelt Caraka-Samhita or Caraka-sa?hita, comprehensive text on ancient Indian medicine credited to Charaka, who was a practitioner of the traditional system of Indian medicine known as Ayurveda.Charaka is thought to have flourished sometime between the 2nd century BCE and the 2nd century CE. Hence, Option 2 is correct.The Charaka-Samhita, in its current form, is believed to have originated in the first century CE.According to ancient Indian medicine studies, the original text was written by Agnivesha, one of six disciples of Ayurvedic scholar Punarvasu Atreya, many centuries ago (the other five disciples were Bhela, Jatukarna, Parashara, Harita, and Ksharapani).Each of the disciples went on to write their own Samhitas, combining both Atreya's ideas and their own understanding of the subject.The Agnivesha-Samhita, written by Agnivesha, was unlike any other in terms of depth and quality.It came to be known as the Charaka-Samhita after Charaka refined and annotated it.The treatise was divided into eight parts, or ashtanga sthanas, by Charaka: sutra, nidana, vimana, sarira, endriya, chikitsa, Kalpa, and Siddha; each section had multiple chapters.